The Company
The AI-driven company behind HelioLiver — detecting cancer early from a simple blood draw, built on a decade of multi-omics research.
The largest prospective, multicenter U.S. trial of its kind.
Read the announcement →The Product
HelioLiver™ LDT — a multi-analyte, epigenomic blood test for early detection of liver cancer (HCC) from a simple blood draw.
Stage I HCC detection — HelioLiver vs ultrasound (CLiMB trial).
See the evidence →For Providers
Surveil at-risk patients with a simple blood draw that fits your existing office workflow.
Set up your office with kits and TRF / EMR ordering.
Order Now →For Patients
Living with a liver condition such as cirrhosis or chronic hepatitis? Ask your doctor about HelioLiver LDT.
Find out if HelioLiver LDT is right for you.
Learn more →AI-driven healthcare company
Helio Genomics is on a mission to make cancer detection simple, affordable, and early — when it is most treatable. With just a blood draw, we are helping more people find cancer at the stage they are most likely to beat it.
Our Mission
For the majority of cancers, 90% of people survive when the disease is detected at an early stage. Yet too many of today’s diagnostics are inconvenient, expensive, and poor at catching cancer early, so too many people are diagnosed when it is already too late. Helio Genomics exists to change that. We focus our work on early detection, when treatment is most effective, and the chances of beating cancer are highest. By transforming how the world screens for cancer, we are working to give everyone the best possible chance.
survival rate when cancer is detected at an early stage, for the majority of cancers1
The Platform
At the heart of Helio Genomics is a multi-analyte, blood-based platform that uses artificial intelligence to read the molecular signals of cancer. It is built to do more than find one disease; it is designed to change how cancer is detected and monitored across the entire patient journey.
We identify proprietary DNA methylation signatures that can reveal cancer as early as Stage I, from a single blood draw — when treatment works best.
Beyond detection, our platform is designed to monitor minimal residual disease, helping clinicians track response and make informed decisions over time.
Machine learning turns complex biomarker data into clear, reliable answers — built on proprietary, patented science developed over nearly a decade.
Our First Commercial Test
HelioLiver LDT is the first test built on the Helio platform, and it is available for clinical use today. It is a simple blood test for the early detection of hepatocellular carcinoma (HCC), the most common form of liver cancer. In the CLiMB trial, HelioLiver detected Stage I liver cancer four times more often than ultrasound, the current standard of care.2
Validated in the CLiMB trial and published in the Journal of Hepatology, May 2026.
Science & Proof
Since 2016, Helio Genomics has pioneered the use of DNA methylation for early cancer detection — with foundational research published in some of the world’s most respected scientific journals.
Founded with a proprietary, patented methylation profile of novel cancer biomarkers.
Early methylation detection research published in Nature and PNAS.
An AI and machine-learning detection method published in Nature Communications.
CLiMB trial results published in the Journal of Hepatology.
Why It Matters
When cancer is caught early, while it is still localised, survival rates are dramatically higher, and far more treatment options are available. Closing the gap between late and early diagnosis — across cancers, beginning with liver — is the heart of what we do.
Five-year survival, liver cancer
Five-year survival, liver cancer
Five-year survival falls sharply from early-stage to advanced-stage liver cancer. Source: SEER Database.3
Partners & Recognition
Bringing groundbreaking cancer detection to patients takes partnership. Helio Genomics works alongside leading healthcare and technology organisations to expand access to early testing — including a strategic commercial partnership with Syneos Health and clinical availability through Quest Diagnostics.
Bring earlier cancer detection into your practice with a simple blood draw.
For Providers →
If you are at higher risk for liver cancer, learn how a simple blood test could help find it earlier.
For Patients →
Explore the platform, the science, and the momentum behind Helio Genomics.
Investor Relations →
Our landmark liver cancer detection study is now peer-reviewed and published.
Read More →
A strategic commercial partnership to accelerate national adoption of HelioLiver.
Read More →
Dr. Bharat Tewarie on where the company and the field are headed.
Watch the Interview →