HelioLiver LDT now available to order through Quest Diagnostics
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AI-driven healthcare company

Saving Lives by Detecting Cancer Early

Helio Genomics is on a mission to make cancer detection simple, affordable, and early — when it is most treatable. With just a blood draw, we are helping more people find cancer at the stage they are most likely to beat it.

Validated in the CLiMB trial Published in the Journal of Hepatology
Helio Genomics scientist analyzing a blood-based sample in the lab
90% survival rate when cancer is
caught at an early stage
more Stage I cancers
detected vs. ultrasound
A single blood draw
Our Mission

Finding Cancer Early Is the Key to Beating It

For the majority of cancers, 90% of people survive when the disease is detected at an early stage. Yet too many of today's diagnostics are inconvenient, expensive, and poor at catching cancer early, so too many people are diagnosed when it is already too late.

Helio Genomics exists to change that. We focus our work on early detection, when treatment is most effective, and the chances of beating cancer are highest. By transforming how the world screens for cancer, we are working to give everyone the best possible chance.

5-Year Survival by Stage at Detection Majority of cancers
Detected early stage 90%
Detected late stage 21%
4× higher Catching cancer early can quadruple the chance of survival. Source: SEER Database.
The Helio Platform

One Platform. A Smarter Way to Detect Cancer.

At the heart of Helio Genomics is a multi-analyte, blood-based platform that uses artificial intelligence to read the molecular signals of cancer. It is built to do more than find one disease; it is designed to change how cancer is detected and monitored across the entire patient journey.

Early Detection

We identify proprietary DNA methylation signatures that can reveal cancer as early as Stage I, from a single blood draw — when treatment works best.

Disease Monitoring

Beyond detection, our platform is designed to monitor minimal residual disease, helping clinicians track response and make informed decisions over time.

Powered by AI

Machine learning turns complex biomarker data into clear, reliable answers — built on proprietary, patented science developed over nearly a decade.

HelioLiver LDT Collection Kit box held in two hands
Available now · Quest Diagnostics
Our First Commercial Test

HelioLiver™ LDT — Our Platform, Proven in the Clinic

HelioLiver LDT is the first test built on the Helio platform, and it is available for clinical use today. It is a simple blood test for the early detection of hepatocellular carcinoma (HCC), the most common form of liver cancer. In the CLiMB trial, HelioLiver detected Stage I liver cancer four times more often than ultrasound, the current standard of care.

44% vs 11%
Stage I HCC detection, HelioLiver vs ultrasound
29% vs 0%
sensitivity for lesions under 2cm
10–14 days
average turnaround time
Validated in the CLiMB trial and published in the Journal of Hepatology, May 2026.
The Science & Proof

Backed by Nearly a Decade of Peer-Reviewed Science

Since 2016, Helio Genomics has pioneered the use of DNA methylation for early cancer detection — with foundational research published in some of the world's most respected scientific journals.

2016

Founded with a proprietary, patented methylation profile of novel cancer biomarkers

2017

Early methylation detection research published in Nature and PNAS

2021

An AI and machine learning detection method was published in Nature Communications

2026

CLiMB trial results published in the Journal of Hepatology

Why It Matters

Why Early Detection Changes Everything

When cancer is caught early, while it is still localised, survival rates are dramatically higher, and far more treatment options are available. Closing the gap between late and early diagnosis — across cancers, beginning with liver — is the heart of what we do.

37% 3%
37%
Early-stage
(localised)
3%
Advanced-stage
(distant)
Five-year survival falls sharply from early-stage to advanced-stage liver cancer · SEER Database
Partners & Recognition

We Collaborate with Leaders in Clinical Care

Bringing groundbreaking cancer detection to patients takes partnership. Helio Genomics works alongside leading healthcare and technology organisations to expand access to early testing — including a strategic commercial partnership with Syneos Health and clinical availability through Quest Diagnostics.

Quest Diagnostics
Microsoft
Syneos Health
American Liver Foundation
For Every Audience

Find Your Path

For Healthcare Providers

Bring earlier cancer detection into your practice with a simple blood draw.

For Providers

For Patients

If you are at higher risk for liver cancer, learn how a simple blood test could help find it earlier.

For Patients

For Investors & Partners

Explore the platform, the science, and the momentum behind Helio Genomics.

Investor Relations
News & Updates

Latest from Helio Genomics

CLiMB Study Published in the Journal of Hepatology

Our landmark liver cancer detection study is now peer-reviewed and published.

Read More

Helio Genomics Partners with Syneos Health

A strategic commercial partnership to accelerate national adoption of HelioLiver.

Read More

Helio Genomics CEO on the Future of Early Cancer Detection

Dr. Bharat Tewarie on where the company and the field are headed.

Watch the Interview

Join Us in Making Cancer a Disease People Survive

From our first test to our next, Helio Genomics is building the future of early cancer detection — one blood draw at a time.