The Company
The AI-driven company behind HelioLiver — detecting cancer early from a simple blood draw, built on a decade of multi-omics research.
The largest prospective, multicenter U.S. trial of its kind.
Read the announcement →The Product
HelioLiver™ LDT — a multi-analyte, epigenomic blood test for early detection of liver cancer (HCC) from a simple blood draw.
Stage I HCC detection — HelioLiver vs ultrasound (CLiMB trial).
See the evidence →For Providers
Surveil at-risk patients with a simple blood draw that fits your existing office workflow.
Set up your office with kits and TRF / EMR ordering.
Order Now →For Patients
Living with a liver condition such as cirrhosis or chronic hepatitis? Ask your doctor about HelioLiver LDT.
Find out if HelioLiver LDT is right for you.
Learn more →For Investors & Media
Recent press coverage and publications highlighting Helio Genomics’ market momentum — from nationwide HelioLiver availability through Quest Diagnostics to the CLiMB trial published in the Journal of Hepatology.
Business Insider covers the expanded provider access for HelioLiver beginning April 2026: healthcare providers with existing Quest accounts can order the blood-based liver cancer test through Quest’s infrastructure of approximately 7,700 patient service centers and EHR integration. CEO Dr. Bharat Tewarie calls it “an important step in widening access to early cancer detection tools,” while Quest’s VP/GM of Oncology Asia Chang notes that “liquid biopsy may play a meaningful role in aiding earlier cancer detection.”
Read the Coverage →In the News
HelioLiver is now commercially available nationwide through Quest's 7,700 patient service centers. CEO Dr. Bharat Tewarie reveals two additional liver cancer tests in development — one to track treatment response, one to monitor recurrence after transplant — and notes Helio submitted its FDA premarket approval application in 2024.
Read the Coverage →This syndicated GlobalData article examines how Helio's blood-based test detects tumor-associated epigenetic signals in cell-free DNA alongside protein biomarkers, noting five-year liver cancer survival drops from 37% for localized disease to just 3% for distant disease.
Read the Coverage →HelioLiver becomes available through Quest Diagnostics starting April 2026, combining cell-free DNA methylation patterns, protein biomarkers, and patient demographics through a proprietary AI algorithm. Testing remains centralized at Helio's CLIA-certified laboratory in West Lafayette, Indiana.
Read the Coverage →Originally published by Pharmaceutical Technology, this analysis argues improved diagnostics could expand the population eligible for curative interventions, positioning the Quest partnership alongside Phase III perioperative immunotherapy trials such as IMbrave050 and CARES-009.
Read the Coverage →The partnership makes HelioLiver widely available across the US from April 2026. The article highlights superior sensitivity to ultrasound for early-stage detection in high-risk individuals, noting liver cancer incidence has tripled since 1980 while 80–90% of eligible adults skip recommended ultrasounds.
Read the Coverage →Helio is exploring AI-driven diagnostic opportunities beyond liver cancer while preparing HelioLiver for broader US availability, positioning its multi-analyte AI platform as a foundation for expanding into additional cancer types.
Read the Coverage →Simply Wall St. analyzes how Quest's partnerships with Helio Genomics and Guardant Health could shape investor returns, with Quest's projected $11.9B revenue by 2028 dependent on growing higher-value preventive and oncology testing. The Helio partnership is described as 'additive to that story.'
Read the Coverage →From April 2026, providers with a Quest account can order HelioLiver through Quest's network of approximately 7,700 patient service centers, integrated into existing provider workflows and EHR systems.
Read the Coverage →LiverRight emphasizes that liver cancer incidence has tripled and mortality doubled, yet 80–90% of at-risk patients don't get screened — and that blood-based liver cancer screening is 'moving toward mainstream clinical adoption at scale.'
Read the Coverage →Becker's reports HelioLiver will be offered through Quest's nationwide provider network starting April 2026 — coverage subsequently syndicated by NewsBreak to 13.9 million readers.
Read the Coverage →HelioLiver achieved 76% sensitivity for early-stage liver cancer in the CLiMB trial versus ultrasound's 47%, and identified 28.6% of tumors under 2cm where ultrasound detected none. The Quest partnership addresses the gap where 80–90% of eligible patients skip biannual ultrasounds.
Read the Coverage →NewsBreak syndicated the Becker's ASC Review announcement to its 13.9 million monthly visitors, amplifying the story from Becker's clinical audience to a mainstream national readership.
Read the Coverage →SAHM Capital syndicates the Simply Wall St. analysis framing the Helio and Guardant partnerships as additive to Quest's growth narrative around higher-margin advanced oncology testing, with projected 2028 revenue of $11.9 billion.
Read the Coverage →